- beauty
- industrial
Interleukin-2
CAS 90804-20-9
Also registered as 2 other CAS numbers
102524-44-7 · 453656-85-4
Concern score
Not assessed — no hazard data yet.
Interleukin-2 in plain language
On cosmetic ingredient lists it appears as “RH-POLYPEPTIDE-12”.
Also known as RH-POLYPEPTIDE-12 · RH-POLYPEPTIDE-25 · RH-POLYPEPTIDE-6 · Human interleukin 2, recombinant non-glycosylated · IL2 non-glycosylated · Recombinant human interleukin 2
Show all 12 names
IL-2 · Interleukin 2 · Interleukin-2 (IL-2) · Interleukin-2, recombinant · Lymphocyte Mitogenic Factor · Thymocyte Stimulating Factor
Used in cosmetics as a skin-conditioning agent.
- Skin conditioning
- Conditioner
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Interleukin-2 appears in these published regulatory listings.
- Found in consumer products
- Industrial
EUCosIngActive3 entries
- rh-Polypeptide-12 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Interleukin-4. It contains a maximum of 153 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416Source →
- rh-Polypeptide-25 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Interleukin- 2. It contains a maximum of 153 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416Source →
- rh-Polypeptide-6 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Interleukin-10. It contains a maximum of 178 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416Source →
USEPAcommercial use observed2 entries
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
- openFDA substance registry classifies this ingredient as protein.Source →
Expert safety opinions
No expert opinion on file for Interleukin-2. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Interleukin-2 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
Reference links (2)
thermofisher.com
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often EPA CPDat has listed Interleukin-2 in a product composition. These are source records, not Greenveil catalog products.
Named organisations
2
Typical roles
Skin conditioningConditioner