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O-tolyl biguanide

CAS 147140-65-6

Also registered as 2 other CAS numbers

92679-92-0 · 93-69-6

O-tolyl biguanide chemical structure

Concern score

Not assessed — no hazard data yet.

O-tolyl biguanide in plain language

What it is

Also known as 1-O-TOLYLBIGUANIDE · 1-(o-Tolyl)biguanide · o-Tolylbiguanide · 1-(diaminomethylidene)-2-(2-methylphenyl)guanidine · N-(2-Methylphenyl)triimidodicarbonic diamide · 1-carbamimidamido-N-(2-methylphenyl)methanimidamide

Show all 17 names

2-Tolylbiguanide · Aliant · BIGUANIDE, 1-o-TOLYL- · Eponoc B · Imidodicarbonimidic diamide, N-(2-methylphenyl)- · N-(2-Methylphenyl)imidodicarbonimidic diamide · Nocceler BG · Sopanox · Vulkacit 1000 · o-Tolyldiguanide · ortho-tolylbiguanide

What it does

Used in cosmetics as an antioxidant.

  • Antioxidant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. O-tolyl biguanide appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • USFDAinactive ingredient database2 entries
    • Route: TOPICAL; Dosage form: SOAP; Potency: 0.02 %w/wSource →
    • Route: TOPICAL; Dosage form: SOLUTION; Potency: 0.01 %w/wSource →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Antioxidant, Catalyst, Chemical reaction regulator.
    • EPA CPDat observed this chemical in 2 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Antioxidant, Catalyst, Chemical reaction regulator.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for O-tolyl biguanide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for O-tolyl biguanide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 23 March 2010

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed O-tolyl biguanide in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

3

Typical roles

Antioxidant
See products using O-tolyl biguanide →

Catalog

Found in these products

Cosmetic and personal-care products that list O-tolyl biguanide are shown first. Their ingredient lists include O-tolyl biguanide; each product's own rating depends on its whole formula, so it is shown on the product page, not here.