# TREHALOSE

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid3048102
Categories: beauty, cleaning, food, pharma
Functions: Humectant, Moisturising, Texturizer, thickener, humectant, stabilizer, sweetener, Flavouring, Conditioner
Identifier: DTXSID3048102

> TREHALOSE: Used in cosmetics as a humectant and a moisturiser. Greenveil chemical-concern score: 40/100 — Moderate concern based on regulatory listings.. Compiled from 8 published data sources.

## Safety assessment

- Chemical concern score: 40/100 — Moderate concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 754 composition records across product categories including Personal care, Batteries.

## Regulatory status

- EU: Active — Listed in CosIng inventory for cosmetic use.
- GLOBAL: NOT SPECIFIED — JECFA evaluation lists ADI NOT SPECIFIED. Functional class: texturizer, thickener, humectant, stabilizer, sweetener.
- GLOBAL: Evaluated — JECFA evaluation record.
- US: commercial use observed — EPA CPDat observed this chemical in 754 composition records across product categories including Personal care, Batteries. EPA CPDat classifies this chemical for functional uses including Humectant, Flavouring and nutrient, Softener and conditioner.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 2 active drug products and 2 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.
- JECFA (Joint FAO/WHO Expert Committee on Food Additives): JECFA evaluation lists ADI NOT SPECIFIED. Functional class: texturizer, thickener, humectant, stabilizer, sweetener. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/4066; JECFA evaluation record. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/4067.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/80292
- EPA Chemical and Products Database (updated September 2018): http://www.unilevermsdsusa.com/MSDSSearch.aspx?fm=0&tb=0
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA National Drug Code Directory (updated 2026-12-31): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- WHO JECFA Database (updated 2026-10-04): https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/4066
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:B8WCK70T7I
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/7427

_Assessed by Greenveil._