What does Calcium sulfide do?

Used in cosmetics as a depilatory.

Is Calcium sulfide safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial
pharma

Calcium sulfide

CAS 1345-11-5

Also registered as 3 other CAS numbers

71685-50-2 · 1447825-12-8 · 20548-54-3

Concern score

Not assessed — no hazard data yet.

Calcium sulfide in plain language

What it is: Also known as Calcium sulfide (CaS) · Calcium sulphide · Bestmade Natural Products Hepar Sulphuris · Crude calcium sulfide · Calcium monosulfide · Hepar sulph
Show all 16 names
Hepar Sulf · Hepar Sulph Calc Kit Refill · Hepar Sulphuris · Hepar sulfuris 30 Special Order · Hepar sulphuris calcareum · Hepar Sulphuris Calcareum 200ck · Hepar Sulphuris Calcareum 30c · Hepar sulphuris calcareum 200C · Hepar sulphuris calcareum 6C · Hepar sulphuris calcareum 7120
What it does: Used in cosmetics as a depilatory.
Depilatory
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Calcium sulfide appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveRestriction: III/23
- Restriction: III/23Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Depilatory.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Depilatory.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 283 active drug products and 328 total products.
- FDA NDC lists this ingredient in 283 active drug products and 328 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Calcium sulfide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Calcium sulfide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2019-12-20
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2030-07-21
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Calcium sulfide in a product composition. These are source records, not Greenveil catalog products.

Source records

328

Typical roles

Depilatory

See products using Calcium sulfide →