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Palmitoyl HEXAPEPTIDE-12

CAS 171263-26-6

Palmitoyl HEXAPEPTIDE-12 chemical structure

Concern score

Not assessed — no hazard data yet.

Palmitoyl HEXAPEPTIDE-12 in plain language

What it is

Also known as 4: PN: US20020197219 PAGE: 2 claimed protein · AKOS027321446 · Biopeptide El · DA-75030 · Jfsqsdaoqlnsqi-dtbjpngvsa-n · Lipopeptide

Show all 15 names

Lipopeptide acetate · N-Palmitoyl-val-gly-val-ala-pro-gly · Pal-val-gly-val-ala-pro-gly · Pal-VGVAPG · Pal-val-gly-val-ala-pro-gly-oh · Palmitoyl Hexapeptide-12 (Liquid) · Palmitoyl Hexapeptide-12 (Powder) · Palmitoyl hexapeptide-12? · UNII-HO4ZT5S86C

What it does

Used in cosmetics as a skin-conditioning agent.

  • Skin conditioning
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Palmitoyl HEXAPEPTIDE-12 appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUCosIngActivePalmitoyl Hexapeptide-12 is the product of the reaction of palmitic acid and Hexapeptide-12
    • Palmitoyl Hexapeptide-12 is the product of the reaction of palmitic acid and Hexapeptide-12Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 4 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    • CIR safety assessment (document tripep032014tent)

      Year not recorded · openFDA Substance reference · Read the source →

Evidence & sources

No graded research studies for Palmitoyl HEXAPEPTIDE-12 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated june 29, 2016

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Palmitoyl HEXAPEPTIDE-12 in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Named organisations

4

Personal care

Typical roles

Skin conditioningConditioner
See products using Palmitoyl HEXAPEPTIDE-12 →

Catalog

Found in these products

Their ingredient lists include Palmitoyl HEXAPEPTIDE-12; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 16 →Find products without it →