# POLYQUATERNIUM-66

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid401358531
Categories: beauty
Functions: Hair conditioning, Hair fixing
Identifier: DTXSID401358531

> POLYQUATERNIUM-66: Used in cosmetics as a hair conditioner and a hair fixative. EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical. Compiled from 2 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

## Regulatory status

- EU: Active — 5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane, polymer with di(hydroxypolymethylene) benzenedicarboxylate and ethylbis(2-hydroxyethyl)methylammonium ethyl sulfate

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/58845
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566

_Assessed by Greenveil._