Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- food
2'-Fucosyllactose
CAS 41536-43-0 · 40/100 · High conf.
Also registered as 5 other CAS numbers
99518-19-1 · 106759-35-7 · 109232-64-6 · 474013-41-7 · 41263-94-9
Concern score
40/100Moderate concern based on regulatory listings.
High confidence
2'-Fucosyllactose in plain language
On cosmetic ingredient lists it appears as “Fucosyllactose”.
Also known as Fucosyllactose · 2'-O-fucosyllactose · 2'-O-L-FUCOSYL-D-LACTOSE · 2'FL · Lactose, 2'-O-FUCOSYL- · 2 inverted exclamation marka-Fucosyl-D-lactose
Show all 18 names
2'-Fucosyllactose (~90%) · 2'-Fucosyllactose - Synthetic · 2-FL · 2/'-FUCOSYLLACTOSE · 2’-FL · 2′-O-Fucosyllactose · 5-O-DMT-thymidine 3' · Cid 170484 · Fuc-a-1,2-Gal-b-1,4-Glc · Lactose, 2′-O-fucosyl- · UNII-XO2533XO8R · V-labs L302
Used in cosmetics as a skin-conditioning agent and a skin protectant.
- Skin conditioning
- Skin protecting
- Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
Why it's flagged
EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
No restrictions found. 2'-Fucosyllactose appears in these published regulatory listings.
EUEFSAEFSA opinion3 entries
- Safety of the extension of use of 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283 (EFSA NDA)Source →
- Statement on the safety of lacto-N-neotetraose and 2'-O-fucosyllactose as novel food ingredients in food supplements for children (EFSA NDA)Source →
- Safety of 2'-O-fucosyllactose as a novel food ingredient pursuant to Regulation (EC) No 258/97 (EFSA NDA)Source →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
Safety of the extension of use of 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283 (EFSA NDA)
2022 · EU EFSA listing · Read the source →
Statement on the safety of lacto-N-neotetraose and 2'-O-fucosyllactose as novel food ingredients in food supplements for children (EFSA NDA)
2015 · EU EFSA listing · Read the source →
Safety of 2'-O-fucosyllactose as a novel food ingredient pursuant to Regulation (EC) No 258/97 (EFSA NDA)
2015 · EU EFSA listing · Read the source →
Evidence & sources
No graded research studies for 2'-Fucosyllactose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- DairyContains · Oral (ingested)
Source: chemindex_name_match
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Found in these products
Their ingredient lists include 2'-Fucosyllactose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
