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Eucalyptol

CAS 8024-52-0 · 60/100 · High conf.

Also registered as 4 other CAS numbers

8024-53-1 · 10458-11-4 · 855347-23-8 · 470-82-6

Eucalyptol chemical structure

Concern score

60/100High concern based on regulatory listings.
High confidence

Eucalyptol in plain language

What it is

Also known as Cineole · 1,8-Cineol · 1,8-Cineole · Cajeputol · Eucaly · Eucalyptole

Show all 21 names

Eucapur · Eukalyptol · P-cineole · Terpan · 1,8-Epoxy-p-menthane · 1,8-Epoxyparamenthane · 1,8-Oxido-p-menthane · NCI-C56575 · P-menthane, 1,8-EPOXY- · Zineol · eucalyptol (1,8-cineole) · eucalyptol (c10h18o) · eucalyptol 0.091% w/v · eucalyptol 0.092% · eucalyptol 0.092% w/v

What it does

Used in cosmetics as a tonic, a fragrance ingredient and a denaturant.

  • Tonic
  • Perfuming
  • Denaturant
  • Flavouring agent
  • Humectant
  • Fragrance
Is it a concern?
High concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 309 composition records across product categories including Cleaning products and household care, Home maintenance, Vehicle.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Eucalyptol appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • USFDAinactive ingredient database7 entries — 4 administration routes
    • Route: OPHTHALMIC; Dosage form: DROPS; Potency: 0.02 %w/wSource →
    • Route: ORAL; Dosage form: CAPSULE; Potency: NASource →
    • Route: NASAL; Dosage form: DROPS; Potency: 0.2 mg/1mlSource →
    • Route: DENTAL; Dosage form: SOLUTION; Potency: NASource →
    • Route: DENTAL; Dosage form: PASTE, DENTIFRICE; Potency: 2.4 %w/wSource →
    • Route: NASAL; Dosage form: SOLUTION; Potency: 0.2 mg/1mlSource →
    • Route: NASAL; Dosage form: JELLY; Potency: 68.5 mgSource →
  • EUEFSAEFSA opinion3 entries
    • Scientific Opinion on the safety and efficacy of aliphatic and alicyclic ethers (chemical group 16) when used as flavourings for all animal species (EFSA FEEDAP)Source →
    • Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) (EFSA AFC)Source →
    • Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010). EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) (EFSA CEF)Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 309 composition records across product categories including Cleaning products and household care, Home maintenance, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Humectant, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 309 composition records across product categories including Cleaning products and household care, Home maintenance, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Humectant, Flavouring and nutrient.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 148 active drug products and 148 total products.
    • FDA NDC lists this ingredient in 148 active drug products and 148 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Scientific Opinion on the safety and efficacy of aliphatic and alicyclic ethers (chemical group 16) when used as flavourings for all animal species (EFSA FEEDAP)

      2012 · EU EFSA listing · Read the source →

    • Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) (EFSA AFC)

      2008 · EU EFSA listing · Read the source →

    • Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010). EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) (EFSA CEF)

      2011 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Eucalyptol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

10 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated september 6, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Eucalyptol in a product composition. These are source records, not Greenveil catalog products.

Source records

309

Named organisations

6

Cleaning products and household careHome maintenanceVehiclePersonal careCleaning and safetyFood and drug

Typical roles

TonicPerfumingDenaturantFlavouring agentHumectantFragrance
See products using Eucalyptol →

Catalog

Found in these products

Their ingredient lists include Eucalyptol; each product's own rating depends on its whole formula, so it is shown on the product page, not here.