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  • industrial
  • pharma

Histamine

CAS 51-45-6

Also registered as 4 other CAS numbers

117932-92-0 · 64422-25-9 · 924364-91-0 · 1416954-63-6

Histamine chemical structure

Concern score

Not assessed — no hazard data yet.

Histamine in plain language

What it is

Also known as .beta.-aminoethylglyoxaline · 2-(1H-Imidazol-5-yl)ethan-1-amine · 2-(1H-imidazol-5-yl)ethanamine · Ergamine · Ergotidine · .beta.-aminoethylimidazole

Show all 24 names

1H-Imidazole-4-ethanamine · 1H-Imidazole-5-ethanamine · 2-(1H-Imidazol-4-yl)ethanamine · 2-(1H-Imidazol-4-yl)ethylamine · 2-(1H-Imidazol-5-yl)ethylamine · 2-(3H-Imidazol-4-yl)ethylamine · 2-(4-IMIDAZOLYL)ETHYLAMINE · 2-(4-Imidazolyl)ethanamine · 2-imidazol-4-ylethylamine · 4-(2-Aminoethyl)-1H-imidazole · 4-IMIDAZOLEETHYLAMINE · 5-IMIDAZOLEETHYLAMINE · Eramin · Free histamine · Imidazole, 4-(2-aminoethyl)- · Imidazole-4-ethylamine · Theramine · beta-Imidazolyl-4-ethylamine

What it does

We don't have a plain-language description for Histamine yet.

Is it a concern?
We haven't assessed a concern score for this ingredient yet.

Regulation

No restrictions found. Histamine appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • USEPAcommercial use observedEPA CPDat observed this chemical in 3 composition records across product categories including Specialty occupational products.
    • EPA CPDat observed this chemical in 3 composition records across product categories including Specialty occupational products.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 5 active drug products and 5 total products.
    • FDA NDC lists this ingredient in 5 active drug products and 5 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Evidence & sources

No graded research studies for Histamine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated 4 December 2007

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (3)
Openfda substance

eurofinsdiscovery.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Histamine in a product composition. These are source records, not Greenveil catalog products.

Source records

5

See products using Histamine →

Catalog

Found in these products

Their ingredient lists include Histamine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 2 →Find products without it →