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Diisobutyl ketone

CAS 1391052-26-8

Also registered as 2 other CAS numbers

958635-42-2 · 108-83-8

Diisobutyl ketone chemical structure

Concern score

Not assessed — no hazard data yet.

Diisobutyl ketone in plain language

What it is

On cosmetic ingredient lists it appears as “2,6-DIMETHYL-4-HEPTANONE”.

Also known as 2,6-DIMETHYL-4-HEPTANONE · Isobutyl ketone · 2,6-Dimethylheptan-4-one · Cognac heptanone · Sec-diisopropyl acetone · Sym-diisopropy lacetone

Show all 25 names

2,6-DIMETHYL-4-HEPTANON · 2,6-Dimethyl-heptan-4-on · 2,6-Dimethylheptan-4-on · 2,6-Dimethylheptanone · 2,6-Dimetil-eptan-4-one · 2,6-dimethylheptane-4-one · 2,6-dimetilheptan-4-ona · 4-Heptanone, 2,6-dimethyl- · Dibk · Di-isobutylcetone · Diisobutilchetone · Diisobutylketon · Diisobutylketone (4-Heptanone, 2,6-dimethyl-) · Heptanone, 2,6-DIMETHYL-, 4- · Isovalerone · Valerone · diisopropylacetone · s-Diisopropylacetone · sym-Diisopropylacetone

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Film former
  • Solvent
  • Fragrance
  • Flavouring
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Diisobutyl ketone appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 265 composition records across product categories including Home maintenance, Raw materials, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Solvent, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 265 composition records across product categories including Home maintenance, Raw materials, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Solvent, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Diisobutyl ketone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diisobutyl ketone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

thegoodscentscompany.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Diisobutyl ketone in a product composition. These are source records, not Greenveil catalog products.

Source records

265

Named organisations

6

Home maintenanceRaw materialsVehicleLaboratory suppliesSpecialty occupational productsConstruction and building materials

Typical roles

PerfumingFilm formerSolventFragranceFlavouring
See products using Diisobutyl ketone →