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Calcium silicate

CAS 11129-16-1 · 40/100 · High conf.

Also registered as 10 other CAS numbers

12612-25-8 · 12616-31-8 · 12707-59-4 · 55584-92-4 · 59787-14-3 · 106857-03-8 · 157090-66-9 · 188674-04-6 · 217468-33-2 · 1344-95-2

Calcium silicate chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Calcium silicate in plain language

What it is

Also known as E-552 · E552 · Huberderm 1000 · Calcium salt silicic acid · calcium bis(trihydroxy(oxido)silane) · Acide silicique, sel de calcium

Show all 27 names

Advacate · CS Lafarge · Calcium Orthosilicate · Calcium hydrosilicate · Calcium monosilicate · Calcium polysilicate · Calcium salt of silicic acid · synthetic Calcium silicate · synthetic nonfibrous Calcium silicate · Calflo E · Calsil · Florite R · Head Cold · Ins NO.552 · INS-552 · Marimet 45 · Micro-Cel · acido silicico, sal de calcio · calcium silicate fibers · calcium silicateintended changes = ic · Calcarea silicata

What it does

Used in cosmetics as an absorbent, a bulking agent and an opacifier. Calcium Silicate is a hydrous or anhydrous silicate with varying proportions of calcium oxide and silica.

  • Absorbent
  • Bulking
  • Opacifying
  • Anticaking agent
  • Thickener
  • Flavouring
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 264 composition records across product categories including Construction and building materials, Raw materials, Pesticides.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Calcium silicate appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Pharma
  • Industrial
  • USFDAinactive ingredient database6 entries
    • Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Potency: 15 mgSource →
    • Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 731 mgSource →
    • Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 600 mgSource →
    • Route: ORAL; Dosage form: TABLET, COATED; Potency: 155 mgSource →
    • Route: ORAL; Dosage form: TABLET; Potency: 146.13 mgSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 40 mgSource →
  • EUCosIngActiveCalcium Silicate is a hydrous or anhydrous silicate with varying proportions of calcium oxide and silica.
    • Calcium Silicate is a hydrous or anhydrous silicate with varying proportions of calcium oxide and silica.Source →
  • EUEFSAEFSA opinionRe-evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives (EFSA ANS)
    • Re-evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives (EFSA ANS)Source →
  • EUEFSAEFSA statementCalcium silicate and silicon dioxide/silicic acid gel added for nutritional purposes to food supplements (EFSA ANS)
    • Calcium silicate and silicon dioxide/silicic acid gel added for nutritional purposes to food supplements (EFSA ANS)Source →
  • GLOBALJECFANOT SPECIFIEDJECFA evaluation lists ADI NOT SPECIFIED. Functional class: anticaking agent.
    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: anticaking agent.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 264 composition records across product categories including Construction and building materials, Raw materials, Pesticides. EPA CPDat classifies this chemical for functional uses including Abrasive, Absorbent, Viscosity modifier.
    • EPA CPDat observed this chemical in 264 composition records across product categories including Construction and building materials, Raw materials, Pesticides. EPA CPDat classifies this chemical for functional uses including Abrasive, Absorbent, Viscosity modifier.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 21 active drug products and 22 total products.
    • FDA NDC lists this ingredient in 21 active drug products and 22 total products.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Re-evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives (EFSA ANS)

      2018 · EU EFSA listing · Read the source →

    • Calcium silicate and silicon dioxide/silicic acid gel added for nutritional purposes to food supplements (EFSA ANS)

      2009 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: anticaking agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Calcium silicate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

10 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated april 3, 2017

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2028-07-26

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

codexalimentarius.net

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Calcium silicate in a product composition. These are source records, not Greenveil catalog products.

Source records

264

Named organisations

6

Construction and building materialsRaw materialsPesticidesHome maintenanceLaboratory suppliesIndustrial products

Typical roles

AbsorbentBulkingOpacifyingAnticaking agentThickenerFlavouring
See products using Calcium silicate →

Catalog

Found in these products

Their ingredient lists include Calcium silicate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 33 →Find products without it →