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  • beauty
  • cleaning

(-)Carophyllene oxide

CAS 11023-55-5

Also registered as 4 other CAS numbers

32095-03-7 · 52209-95-7 · 105120-46-5 · 1139-30-6

(-)Carophyllene oxide chemical structure

Concern score

Not assessed — no hazard data yet.

(-)Carophyllene oxide in plain language

What it is

On cosmetic ingredient lists it appears as “Caryophyllene oxide”.

Also known as Caryophyllene oxide · .beta.-caryophyllene oxide · (-)-beta-caryophyllene epoxide · (-)-.beta.-caryophyllene epoxide · (-)-caryophyllene oxide · 4.BETA.,5.ALPHA.-EPOXYCARYOPHYLLENE

Show all 19 names

Caryophyllene 4.BETA.,5.ALPHA.-EPOXIDE · Caryophyllene 4.BETA.,5.ALPHA.-OXIDE · Epoxide caryophyllene · Trans-caryophyllene oxide · (-)-Epoxydihydrocaryophyllene · (-)-β-Caryophyllene epoxide · (-)-β-Caryophyllene oxide · Beta-caryophyllene oxide · Caryophylleneoxide · Caryophylene oxide · Epoxycaryophyllene · beta-Caryophyllene epoxide · epoxide

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Fragrance
  • Flavouring
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. (-)Carophyllene oxide appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 2 composition records across product categories including Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for (-)Carophyllene oxide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for (-)Carophyllene oxide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated February 8, 2019

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed (-)Carophyllene oxide in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

5

Cleaning products and household care

Typical roles

PerfumingFragranceFlavouring
See products using (-)Carophyllene oxide →