What does Hydroxycortisone succinate do?

Used in cosmetics as a skin-conditioning agent.

Is Hydroxycortisone succinate safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Hydroxycortisone succinate

CAS 30210-46-9

Also registered as 2 other CAS numbers

53623-76-0 · 2203-97-6

Hydroxycortisone succinate chemical structure

Concern score

Not assessed — no hazard data yet.

Hydroxycortisone succinate in plain language

What it is: Also known as Hydrocortisone hydrogen succinate · Hydrocortisone succinate · Cortisol 21-hemisuccinate · Hydrocortisone hemisuccinate anhydrous · Cortisol 21-(HYDROGEN succinate) · Cortisol succinate
Show all 15 names
Cortisol hemisuccinate · Cortisol, 21-(hydrogen succinate) · hydrogen succinate Cortisol · Hydrocortisone 21-(hydrogen succinate) · Hydrocortisone 21-O-beta-carbonylpropionic acid · Hydrocortisone 21-hemisuccinate · MLS000028530 · MLS001146928 · Oristar hcshs
What it does: Used in cosmetics as a skin-conditioning agent.
Skin conditioning
Conditioner
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Hydroxycortisone succinate appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveRestriction: II/300
- Restriction: II/300Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Hydroxycortisone succinate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Hydroxycortisone succinate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2020-08-31
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Hydroxycortisone succinate in a product composition. These are source records, not Greenveil catalog products.

Named organisations

Typical roles

Skin conditioningConditioner

See products using Hydroxycortisone succinate →