# 1,3,5,7,9,11,13,15-Octakis(2-methylpropyl)pentacyclo[9.5.1.1~3,9~.1~5,15~.1~7,13~]octasiloxane

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid40944777
Categories: beauty, industrial
Functions: Nail conditioning, Conditioner
Identifier: DTXSID40944777

> 1,3,5,7,9,11,13,15-Octakis(2-methylpropyl)pentacyclo[9.5.1.1~3,9~.1~5,15~.1~7,13~]octasiloxane: Used in cosmetics as a nail conditioning agent. EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. Compiled from 3 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.

## Regulatory status

- EU: Active — Isobutyl Polysilsesquioxane is a resinous material composed of a mixture of three-dimensional siloxane polymers and oligomers with cage structures. For the oligomers, each silicon atom in the polysilsesquioxane is connected via oxygen atoms to three other silicon atoms and can be represented by the empirical formulation RSiO3/2 where R represents the isobutyl group. For the larger polymeric polysilsesquioxanes, some of the silicon atoms are not connected to other silicon atoms and instead have a silanol (SiOH) group. Isobutyl Polysilsesquioxane is prepared by the hydrolysis and condensation of 2-methylpropyl trimethoxysilane.
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/93230
- EPA Chemical and Products Database (updated 2019-12-20): https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=93230
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566

_Assessed by Greenveil._