Food use
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
- food
- pharma
Protamine sulfate
CAS 9009-65-8
Concern score
Not assessed — no hazard data yet.
Protamine sulfate in plain language
Also known as sulfates Protamines · Novo protamine sulfate · Protamine sulphate · protamine salt Sulfuric acid · protamine sulfate 10 mg/ml
Show all 6 names
Protamini sulfas
Used in cosmetics as a skin-conditioning agent.
- Skin conditioning
- Conditioner
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Protamine sulfate appears in these published regulatory listings.
- In marketed US drugs
- Inactive ingredient in US drugs
- Found in consumer products
- Pharma
- Food
USFDAinactive ingredient database4 entries — 3 administration routes
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 13 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- EPA CPDat observed this chemical in 13 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 5 active drug products and 5 total products.
- FDA NDC lists this ingredient in 5 active drug products and 5 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as structurallydiverse.
- openFDA substance registry classifies this ingredient as structurallydiverse.Source →
Expert safety opinions
No expert opinion on file for Protamine sulfate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Protamine sulfate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated 2020-08-31
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
- Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often EPA CPDat has listed Protamine sulfate in a product composition. These are source records, not Greenveil catalog products.
Source records
13
Named organisations
4
Food and drug
Typical roles
Skin conditioningConditioner