- beauty
- industrial
Calcium pidolate
CAS 31377-05-6
Concern score
Not assessed — no hazard data yet.
Calcium pidolate in plain language
On cosmetic ingredient lists it appears as “Calcium PCA”.
Also known as Calcium PCA · Calcium bis · 5-OXO-L-PROLINE calcium salt · Calcium l-pyroglutamate · L-calcium pidolate · L-proline, 5-OXO-, calcium salt (2:1)
Show all 19 names
Calcium salt l-pyrrolidone carboxylic acid · Pidolic acid calcium salt (2:1) · Proline, 5-OXO-, calcium salt (2:1), l- · Calcidone · Calcium oxoproline · Calcium (S)-5-oxopyrrolidine-2-carboxylate · Calcium L-pidolate · Calcium bis(5-oxo-L-prolinate) · Efical · Ibercal (TN) · L-Proline, 5-Oxo, Calcium Salt (2:1) · UNII-7Y2LVU5EKK · calcium;(2S)-5-oxopyrrolidine-2-carboxylate
Used in cosmetics as a humectant and a skin-conditioning agent.
- Humectant
- Skin conditioning
- Conditioner
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Calcium pidolate appears in these published regulatory listings.
- Found in consumer products
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Calcium pidolate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Calcium pidolate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated 2019-12-20
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often EPA CPDat has listed Calcium pidolate in a product composition. These are source records, not Greenveil catalog products.
Named organisations
1
Typical roles
HumectantSkin conditioningConditioner
Found in these products
Cosmetic and personal-care products that list Calcium pidolate are shown first. Their ingredient lists include Calcium pidolate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
