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Trimethylsilyl ((trimethylsilyl)oxy)acetate

CAS 33581-77-0

Trimethylsilyl ((trimethylsilyl)oxy)acetate chemical structure

Concern score

Not assessed — no hazard data yet.

Trimethylsilyl ((trimethylsilyl)oxy)acetate in plain language

What it is

On cosmetic ingredient lists it appears as “Trimethylsilyl trimethylsiloxy glycolate”.

Also known as Trimethylsilyl trimethylsiloxy glycolate · trimethylsilyl 2-trimethylsilyloxyacetate · Acetic acid, (trimethylsiloxy)-, trimethylsilyl ester · Glycolic acid, (2TMS) · Glycolic acid, 2TMS derivative · bis-TMS Glycolic acid

Show all 13 names

di-TMS Glycolic acid · IBA58177 · Maeqowmwocexkp-uhfffaoysa-n · Trimethylsilyl(trimethylsiloxy)acetate · Trimethylsilyl trimethylsiloxyacetate · UNII-WY41M9TKT0 · trimethylsilyl 2-((trimethylsilyl)oxy)acetate

What it does

Used in cosmetics as a skin-conditioning agent. Acetic acid, [(trimethylsilyl)oxy]-, trimethylsilyl ester.

  • Skin conditioning
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Trimethylsilyl ((trimethylsilyl)oxy)acetate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveAcetic acid, [(trimethylsilyl)oxy]-, trimethylsilyl ester
    • Acetic acid, [(trimethylsilyl)oxy]-, trimethylsilyl esterSource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Trimethylsilyl ((trimethylsilyl)oxy)acetate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Trimethylsilyl ((trimethylsilyl)oxy)acetate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2019-12-20

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Trimethylsilyl ((trimethylsilyl)oxy)acetate in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Skin conditioningConditioner
See products using Trimethylsilyl ((trimethylsilyl)oxy)acetate →