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Ethinyl estradiol

CAS 77538-56-8

Also registered as 3 other CAS numbers

406932-93-2 · 1050678-65-3 · 57-63-6

Ethinyl estradiol chemical structure

Concern score

Not assessed — no hazard data yet.

Ethinyl estradiol in plain language

What it is

On cosmetic ingredient lists it appears as “Ethinylestradiol”.

Also known as Ethinylestradiol · 17alpha-Ethinylestradiol · 17-ETHINYLESTRADIOL · 17alpha-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol · 19-NORPREGNA-1,3,5(10)-TRIEN-20-YNE-3,17-DIOL, (17.ALPHA.)- · 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol

Show all 104 names

Ethinyloestradiol · (17α)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol · 17- alpha-ethinylestradiol · 17-Ethinyl-3,17-estradiol · 17-alpha-estradiol · 17-alpha-ethynylestradiol · 17alpha-Ethynylestradiol · 17α-Ethinyl estradiol · 17α-Ethinyl estradiol (EE2) · 19-NOR-17.ALPHA.-PREGNA-1,3,5(10)-TRIEN-20-YNE-3,17-DIOL · 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)- · 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17α)- · Amenoron · Dyloform · Estinyl · Estigyn · Ethidol · Ethynyl estradiol · Ethynylestradiol · Eticyclin · Eticyclol · Etinestrol · Etinoestryl · Feminone · Ginestrene · Inestra · Lynoral · Progynon C · Alesse component ethinyl estradiol · Altavera component ethinyl estradiol · Aranelle component ethinyl estradiol · Beyaz component ethinyl estradiol · Cryselle component ethinyl estradiol · Cyclessa component ethinyl estradiol · Desogen component ethinyl estradiol · Estrostep fe component ethinyl estradiol · Femcon fe component ethinyl estradiol · Femhrt component ethinyl estradiol · Introvale component ethinyl estradiol · Kariva component ethinyl estradiol · Kelnor component ethinyl estradiol · Kurvelo component ethinyl estradiol · Levlite component ethinyl estradiol · Levonest component ethinyl estradiol · Lo loestrin fe component ethinyl estradiol · Loseasonique component ethinyl estradiol · Lybrel component ethinyl estradiol · Mircette component ethinyl estradiol · Norquest fe component ethinyl estradiol · Nuvaring component ethinyl estradiol · Orsythia component ethinyl estradiol · Ortho tri-cyclen component ethinyl estradiol · Ortho-cept component ethinyl estradiol · Ovral component ethinyl estradiol · Preven component ethinyl estradiol · Previfem component ethinyl estradiol · Quasense component ethinyl estradiol · Safyral component ethinyl estradiol · Seasonale component ethinyl estradiol · Seasonique component ethinyl estradiol · Sprintec component ethinyl estradiol · Tri lo sprintec component ethinyl estradiol · Tri-legest fe component ethinyl estradiol · Tri-previfem component ethinyl estradiol · Tri-sprintec component ethinyl estradiol · Velivet component ethinyl estradiol · Yasmin component ethinyl estradiol · Yaz component ethinyl estradiol · Annovera component ethinyl estradiol · Aviane component ethinyl estradiol · Bekyree component ethinyl estradiol · Brevicon component ethinyl estradiol · Elifemme component ethinyl estradiol · Enpresse component ethinyl estradiol · Enskyce component ethinyl estradiol · Femlyv component ethinyl estradiol · Isibloom component ethinyl estradiol · Lessina component ethinyl estradiol · Levora component ethinyl estradiol · Lo minastrin fe component ethinyl estradiol · Marlissa component ethinyl estradiol · Minastrin 24 fe component ethinyl estradiol · Nordette component ethinyl estradiol · Norinyl component ethinyl estradiol · Pimtrea component ethinyl estradiol · Portia component ethinyl estradiol · Quartette component ethinyl estradiol · Setlakin component ethinyl estradiol · Taytulla component ethinyl estradiol · Triphasil component ethinyl estradiol · Trivora component ethinyl estradiol · Twirla component ethinyl estradiol · Vienva component ethinyl estradiol · Viorele component ethinyl estradiol · Volnea component ethinyl estradiol · Vyfemla component ethinyl estradiol · Xulane component ethinyl estradiol · Zovia component ethinyl estradiol

What it does

Used in cosmetics as a skin-conditioning agent.

  • Skin conditioning
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Ethinyl estradiol appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Pharma
  • Food
  • EUCosIngActiveRestriction: II/260
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 46 active drug products and 47 total products.
    • FDA NDC lists this ingredient in 46 active drug products and 47 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Ethinyl estradiol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Ethinyl estradiol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated March 8, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (33)
Openfda substance

dailymed.nlm.nih.gov

Openfda substance

accessdata.fda.gov

Openfda substance

accessdata.fda.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

accessdata.fda.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

dailymed.nlm.nih.gov

+ 21 more not shown

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Ethinyl estradiol in a product composition. These are source records, not Greenveil catalog products.

Source records

47

Typical roles

Skin conditioningConditioner
See products using Ethinyl estradiol →