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Fructose

CAS 6347-01-9 · 0/100 · High conf.

Also registered as 7 other CAS numbers

10489-79-9 · 69-67-0 · 3812-57-5 · 10597-68-9 · 149014-33-5 · 196419-06-4 · 57-48-7

Fructose chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (EU CosIng).
High confidence

Fructose in plain language

What it is

Also known as Sugar fruit fine · D-Fructose · Levulose · Nevulose · Advantose FS 95 · D-(-)-Levulose

Show all 15 names

D-ARABINO-HEX-2-ULOPYRANOSE · D-Arabino-2-Hexulose · Fructose, D- · Fruit sugar · High Fructose Corn Syrup · d(-)fructose · pura fructosa · fructosum / laevulosum · Fructose (constituent of cranberry liquid preparation)

What it does

Used in cosmetics as a humectant.

  • Humectant
  • Thickener
  • Solvent
  • Fragrance
  • Flavouring
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 110 composition records across product categories including Construction and building materials, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Fructose appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • USFDAinactive ingredient database10 entries — 3 administration routes
    • Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 205 mgSource →
    • Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Potency: 2625 mg/5mlSource →
    • Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 6000 mgSource →
    • Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 13872 mgSource →
    • Route: ORAL; Dosage form: SUSPENSION; Potency: 20 mg/1mlSource →
    • Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: NASource →
    • Route: ORAL; Dosage form: SYRUP; Potency: 1732.5 mg/5mlSource →
    • Route: ORAL; Dosage form: TABLET; Potency: 64.92 mgSource →
    • Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 72 mgSource →
    • Route: RECTAL; Dosage form: SOLUTION; Potency: 0.67 %w/vSource →
  • USFDAlisted in openFDA substance2 entries
    • openFDA substance registry classifies this ingredient as concept.Source →
    • openFDA substance registry classifies this ingredient as chemical.Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 110 composition records across product categories including Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Flavouring and nutrient, Fragrance.
    • EPA CPDat observed this chemical in 110 composition records across product categories including Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Flavouring and nutrient, Fragrance.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 19 active drug products and 19 total products.
    • FDA NDC lists this ingredient in 19 active drug products and 19 total products.Source →

Expert safety opinions

No expert opinion on file for Fructose. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Fructose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Fructose in a product composition. These are source records, not Greenveil catalog products.

Source records

110

Named organisations

6

Construction and building materialsPersonal care

Typical roles

HumectantThickenerSolventFragranceFlavouring
See products using Fructose →

Catalog

Found in these products

Their ingredient lists include Fructose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Fructose in the catalog.