beauty
cleaning
food
pharma

Diisopropyl adipate

CAS 121879-14-9 · 40/100 · High conf.

Also registered as 1 other CAS number

6938-94-9

Concern score

40/100Moderate concern based on regulatory listings.

High confidence

Diisopropyl adipate in plain language

What it is: Also known as Ceraphyl 230 · Diisopropyl ester adipic acid · Disopropyl adipate · Dipropan-2-yl hexanedioate · Adipinsaeure-diisopropylester · Adipate de diisopropyle
Show all 19 names
BIS(1-METHYLETHYL)HEXANEDIOATE · Crodamol DA · Di-isopropyl adipate · Hexanedioic acid, 1,6-BIS(1-METHYLETHYL) ester · Hexanedioic acid, bis(1-methylethyl) ester · Isopropyl adipate · Prodipate · Schercemol DIA · Standamul DIPA · Tegester 504-D · Wickenol 116 · adipato de diisopropilo · beta dia
What it does: Used in cosmetics as an emollient, a solvent and a skin-conditioning agent.
Emollient
Solvent
Skin conditioning
Plasticiser
Fragrance
Flavouring agent
Is it a concern?: Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 402 composition records across product categories including Personal care, Food and drug, Cleaning products and household care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Diisopropyl adipate appears in these published regulatory listings.

Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food

USFDAinactive ingredient database7 entries — 2 administration routes
- Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 170 mgSource →
- Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 150 mgSource →
- Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 250 mgSource →
- Route: TOPICAL; Dosage form: AEROSOL, FOAM; Maximum daily exposure: 200 mgSource →
- Route: TOPICAL; Dosage form: SPRAY; Maximum daily exposure: 360 mgSource →
- Route: TRANSDERMAL; Dosage form: GEL; Potency: 1.5 %w/wSource →
- Route: TOPICAL; Dosage form: SOLUTION; Maximum daily exposure: 815 mgSource →
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
- JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 402 composition records across product categories including Personal care, Food and drug, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Solvent, Softener and conditioner, Plasticizer.
- EPA CPDat observed this chemical in 402 composition records across product categories including Personal care, Food and drug, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Solvent, Softener and conditioner, Plasticizer.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
JECFA
Joint FAO/WHO Expert Committee on Food Additives
- JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
  Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Diisopropyl adipate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated february 2, 2018
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
WHO JECFA Database
regulatory · updated 2026-10-04
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Diisopropyl adipate in a product composition. These are source records, not Greenveil catalog products.

Source records

402

Named organisations

Personal careFood and drugCleaning products and household care

Typical roles

EmollientSolventSkin conditioningPlasticiserFragranceFlavouring agent

See products using Diisopropyl adipate →

Catalog

Found in these products

Their ingredient lists include Diisopropyl adipate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 99 →Find products without it →