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Diacetin

CAS 1300-63-6

Also registered as 3 other CAS numbers

29860-16-0 · 1202865-19-7 · 25395-31-7

Concern score

Not assessed — no hazard data yet.

Diacetin in plain language

What it is

Also known as Diacetain glycerol · Diacetin glycerol · Glycerol diacetate · Glyceryl diacetate · 1,2,3-Propanetriol, diacetate · 1,3-Di(acetate) de glycerol

Show all 13 names

1,​2,​3-​Propanetriol, diacetate · Acetin, di- · Diacetylglycerol · Estol 1582 · Glycerol diactate · Glycerin-1,3-di(acetat) · Glycerol 1,3-di(acetate)

What it does

Used in cosmetics as a solvent.

  • Solvent
  • Fragrance
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Diacetin appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Solvent, Fragrance.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Solvent, Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as mixture.
    • openFDA substance registry classifies this ingredient as mixture.Source →

Expert safety opinions

No expert opinion on file for Diacetin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diacetin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Diacetin in a product composition. These are source records, not Greenveil catalog products.

Source records

1

Named organisations

5

Laboratory supplies

Typical roles

SolventFragrance
See products using Diacetin →