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  • beauty
  • industrial
  • pharma

Tioxolone

CAS 4991-65-5

Tioxolone chemical structure

Concern score

Not assessed — no hazard data yet.

Tioxolone in plain language

What it is

Also known as 6-Hydroxy-1,3-benzoxathiol-2-one · Thioxolone · 6-Hydroxy-2H-1,3-benzoxathiol-2-one · 1,3-Benzoxathiol-2-one, 6-hydroxy- · 6-Hydro-2-oxo-1,3-benzoxathiole · 6-hydroxy-1,3(2H)-benzoxathiol-2-one

Show all 13 names

Camyna · D10AB03 · Thioxalone · Thyioxolone · Tioxolon · Tioxolona · Tioxolonum

What it does

Used in cosmetics as an astringent.

  • Astringent
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Tioxolone appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Astringent.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Astringent.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 5 drug products and 5 package presentations.
    • FDA NDC lists this ingredient in 5 drug products and 5 package presentations.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Tioxolone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Tioxolone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2020-08-31

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2028-02-03

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Tioxolone in a product composition. These are source records, not Greenveil catalog products.

Source records

5

Typical roles

Astringent
See products using Tioxolone →