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Polyaminopropyl biguanide

CAS 133029-32-0

Concern score

Not assessed — no hazard data yet.

Polyaminopropyl biguanide in plain language

What it is: Also known as Papb · Acticide phb 20
What it does: Used in consumer products as a preservative, an antiperspirant and an antimicrobial.
Preservative
Antiperspirant
Antimicrobial
Is it a concern?: We haven't assessed a concern score for this ingredient yet.

Regulation

No restrictions found. Polyaminopropyl biguanide appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning

USEPAcommercial use observedEPA CPDat observed this chemical in 405 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Preservative, Biocide, Antiperspirant.
- EPA CPDat observed this chemical in 405 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Preservative, Biocide, Antiperspirant.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 4 active drug products and 4 total products.
- FDA NDC lists this ingredient in 4 active drug products and 4 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
- openFDA substance registry classifies this ingredient as polymer.Source →

Expert safety opinions

No expert opinion on file for Polyaminopropyl biguanide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Polyaminopropyl biguanide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

EPA Chemical and Products Database
exposure · updated September 2017
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →

Reference links (1)

Openfda substance

en.wikipedia.org

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Polyaminopropyl biguanide in a product composition. These are source records, not Greenveil catalog products.

Source records

405

Named organisations

Personal care

Typical roles

PreservativeAntiperspirantAntimicrobial

See products using Polyaminopropyl biguanide →

Catalog

Found in these products

Their ingredient lists include Polyaminopropyl biguanide; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 44 →Find products without it →