What does Mangiferin do?

Used in cosmetics as a skin protectant.

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Mangiferin

CAS 491-63-4

Also registered as 7 other CAS numbers

69959-35-9 · 99331-60-9 · 173070-82-1 · 233599-15-0 · 478483-43-1 · 906328-94-7 · 4773-96-0

Concern score

Not assessed — no hazard data yet.

Mangiferin in plain language

What it is: Also known as Mangifera indica bark dry extract · Chinonin · Alpizarin · Alpizarine · Aphloiol · Hedysarid
Show all 10 names
9H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy- · Chinomin · Mangiferin Mangifera indica · Xanthone-c-glucoside
What it does: Used in cosmetics as a skin protectant.
Skin protecting
Humectant
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Mangiferin appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Mangiferin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Mangiferin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2019-12-20
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (1)

Openfda substance

chemicalland21.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Mangiferin in a product composition. These are source records, not Greenveil catalog products.

Named organisations

Typical roles

Skin protectingHumectant

See products using Mangiferin →