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Palmitoyl isoleucine

CAS 101541-04-2

Also registered as 1 other CAS number

54617-29-7

Palmitoyl isoleucine chemical structure

Concern score

Not assessed — no hazard data yet.

Palmitoyl isoleucine in plain language

What it is

Also known as (2S,3S)-2-(hexadecanoylamino)-3-methylpentanoic acid · N-Hexadecanoyl-L-isoleucine · Epitope ID:2281338 · Isoleucine, N-(1-oxohexadecyl)- · L-Isoleucine, N-(1-oxohexadecyl)- · N-Palmitoyl-L-isoleucine

Show all 12 names

N-hexadecanoyl-isoleucine · N-palmitoyl isoleucine · UNII-957769006D · Voluform · palmitoyl-L-isoleucine · starbld0010583

What it does

Used in cosmetics as a skin protectant.

  • Skin protecting
  • Humectant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Palmitoyl isoleucine appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveL-Isoleucine, N-(1-oxohexadecyl)-
  • USEPAcommercial use observedEPA CPDat observed this chemical in 16 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant.
    • EPA CPDat observed this chemical in 16 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Palmitoyl isoleucine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Palmitoyl isoleucine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Palmitoyl isoleucine in a product composition. These are source records, not Greenveil catalog products.

Source records

16

Named organisations

3

Personal care

Typical roles

Skin protectingHumectant
See products using Palmitoyl isoleucine →

Catalog

Found in these products

Cosmetic and personal-care products that list Palmitoyl isoleucine are shown first. Their ingredient lists include Palmitoyl isoleucine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1 →Find products without it →