- beauty
- food
- pharma
Valproic acid
CAS 875128-67-9
Also registered as 1 other CAS number
99-66-1
Concern score
Not assessed — no hazard data yet.
Valproic acid in plain language
Also known as 2-Propylpentanoic acid · Pentanoic acid, 2-PROPYL · Valproic acid extended release · 2,2-Di-n-propylacetic acid · 2-Propan-1-ylpentanoic acid · 2-Propylvaleric acid
Show all 31 names
2-n-Propyl-n-valeric acid · 4-Heptanecarboxylic acid · Acide valproique · Acido valproico · Acidum valproicum · Convulex · Depakene · Depakine · Depakine-chrono · Di-n-propylacetic acid · Di-n-propylessigsaure · Dipropylacetic acid · Kyselina 2-propylvalerova · Mylproin · Myproic Acid · Propylvaleric acid · Pentanoic acid, 2-propyl- · Pentanoic acid, 2-propyl- · Sigma V 0033000 · Stavzor · Vpa · Valproate (Valproic acid) · n-DPA · n-Dipropylacetic acid · valproate
Used in cosmetics as a skin-conditioning agent.
- Skin conditioning
- Conditioner
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Valproic acid appears in these published regulatory listings.
- In marketed US drugs
- Found in consumer products
- Pharma
- Food
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Pharmaceutical.
- EPA CPDat observed this chemical in 2 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Pharmaceutical.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 25 active drug products and 26 total products.
- FDA NDC lists this ingredient in 25 active drug products and 26 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Valproic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Valproic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated November 2007
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2027-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often FDA National Drug Code directory has listed Valproic acid in a product composition. These are source records, not Greenveil catalog products.
Source records
26
Typical roles
Skin conditioningConditioner