What does Ethyl 3-HYDROXYBUTYRATE do?

Used in cosmetics as a fragrance ingredient.

Is Ethyl 3-HYDROXYBUTYRATE safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Ethyl 3-HYDROXYBUTYRATE

CAS 35608-64-1

Also registered as 1 other CAS number

5405-41-4

Ethyl 3-HYDROXYBUTYRATE chemical structure

Concern score

Not assessed — no hazard data yet.

Ethyl 3-HYDROXYBUTYRATE in plain language

What it is: Also known as Butanoic acid, 3-HYDROXY-, ethyl ester · DL-3-HYDROXY-N-BUTYRATE ethyl ester · Ethyl (1)-3-HYDROXYBUTYRATE · Ethyl DL-3-HYDROXYBUTYRATE · Ethyl 3-hydroxybutanoate · Grape butyrate
Show all 17 names
(+/-)-3-HYDROXYBUTANOIC acid ethyl ester · (+/-)-ethyl 3-HYDROXYBUTYRATE · (±)-3-HYDROXYBUTANOIC acid ethyl ester · (±)-ethyl 3-HYDROXYBUTYRATE · 3-HYDROXYBUTANOIC acid ethyl ester · 3-HYDROXYBUTYRIC acid ethyl ester · Butyric acid, 3-hydroxy-, ethyl ester · Ethyl (+/-)-3-HYDROXYBUTANOATE · Ethyl (±)-3-HYDROXYBUTANOATE · Ethyl (R)-(-)-3-hydroxybutyrate · Ethyl beta-hydroxybutyrate
What it does: Used in cosmetics as a fragrance ingredient.
Perfuming
Solvent
Fragrance
Flavouring
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Ethyl 3-HYDROXYBUTYRATE appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient, Solvent.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient, Solvent.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Ethyl 3-HYDROXYBUTYRATE. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Ethyl 3-HYDROXYBUTYRATE yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated February 8, 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Ethyl 3-HYDROXYBUTYRATE in a product composition. These are source records, not Greenveil catalog products.

Named organisations

Typical roles

PerfumingSolventFragranceFlavouring

See products using Ethyl 3-HYDROXYBUTYRATE →