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Sorbitan trioleate

CAS 2599-45-3

Also registered as 10 other CAS numbers

70024-41-8 · 1338-44-9 · 5960-06-5 · 61090-27-5 · 120913-10-2 · 171286-91-2 · 368449-42-7 · 917485-38-2 · 917485-40-6 · 26266-58-0

Sorbitan trioleate chemical structure

Concern score

Not assessed — no hazard data yet.

Sorbitan trioleate in plain language

What it is

Also known as Anhydrosorbitol trioleate · Sorbitan, TRI-(9Z)-9-OCTADECENOATE · Sorbitan, TRI-9-OCTADECENOATE · SPAN-85 · SPAN85 · Anhydro-o-glucitol trioleate

Show all 27 names

Arlacel 85 · Alkamuls STO · Anhydro-D-glucitol trioleate · Anhydro-D-glucitoltrioleat · Crill 5 · Dehymuls STO · Emasol 430 · Emsorb 2503 · Glycomul TO · Ionet S 85 · Liposorb TO · Nissan nonion OP 85 · Nissan nonion OP 85R · Op 85R · Protachem STO · Rheodol SP 030 · Span 85 · Sorbitan, tri-9-octadecenoate, (Z,Z,Z)- · Te 33 · Trioleato de sorbitano · MF59 component SPAN85

What it does

Used in cosmetics as an emulsifier.

  • Emulsifying
  • Emulsifier
  • Surfactant
  • Fragrance
  • Lubricant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Sorbitan trioleate appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • USFDAinactive ingredient database5 entries — 2 administration routes
    • Route: ORAL; Dosage form: CAPSULE; Potency: NASource →
    • Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 12 mgSource →
    • Route: ORAL; Dosage form: TABLET; Potency: NASource →
    • Route: RESPIRATORY (INHALATION); Dosage form: AEROSOL, METERED; Potency: NASource →
    • Route: RESPIRATORY (INHALATION); Dosage form: AEROSOL, SPRAY; Potency: 0.86 %w/wSource →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 110 composition records across product categories including Furniture and furnishings, Food and drug, Raw materials. EPA CPDat classifies this chemical for functional uses including Emulsifier, Surfactant (surface active agent), Fragrance.
    • EPA CPDat observed this chemical in 110 composition records across product categories including Furniture and furnishings, Food and drug, Raw materials. EPA CPDat classifies this chemical for functional uses including Emulsifier, Surfactant (surface active agent), Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Sorbitan trioleate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Sorbitan trioleate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

sciencedirect.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Sorbitan trioleate in a product composition. These are source records, not Greenveil catalog products.

Source records

110

Named organisations

6

Furniture and furnishingsFood and drugRaw materialsPersonal careIndustrial products

Typical roles

EmulsifyingEmulsifierSurfactantFragranceLubricant
See products using Sorbitan trioleate →

Catalog

Found in these products

Cosmetic and personal-care products that list Sorbitan trioleate are shown first. Their ingredient lists include Sorbitan trioleate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.