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Sodium cocoyl isethionate

CAS 85681-84-1 · 0/100 · High conf.

Also registered as 4 other CAS numbers

131015-91-3 · 218433-02-4 · 58969-27-0 · 61789-32-0

Sodium cocoyl isethionate chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe when formulated as directed; EU CosIng).
High confidence

Sodium cocoyl isethionate in plain language

What it is

Also known as Sodium cocoyl isetionate · Sodium;2-butanoyloxyethanesulfonate · Coconut fatty acid, 2-SULFOETHYL ester, sodium salt · Fatty acids, coconut oil, sulfoethyl esters, sodium salts · Sodium isethionate coconut ester · sodium 2-butanoyloxyethanesulfonate

Show all 18 names

Arlatone SCI · Coco fatty acids, 2-sulfoethyl esters, sodium salts · Coconut oil acids, 2-sulfoethyl ester, sodium salt · Coconutoilacidester of sodiumisethionate · FS55424 · Fatty acids, coco, 2-sulfoethyl esters, sodium salts · Igepon AC-78 · Sodium coco fatty acid isethionate · Sodium cocoyl isethionate, 83-88% · Wyhcvlbwwxvcem-uhfffaoysa-m · acidos grasos, coco, 2-sulfoetil esteres, sales de sodio · sodium cocoyl isothionate

What it does

Used in cosmetics as a cleansing agent and a hair conditioner.

  • Cleansing
  • Hair conditioning
  • Surfactant
  • Conditioner
  • Cleaning agent
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 1274 composition records across product categories including Cleaning products and household care, Personal care, Raw materials.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Sodium cocoyl isethionate appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveFatty acids, coco, 2-sulfoethyl esters, sodium salts
    • Fatty acids, coco, 2-sulfoethyl esters, sodium saltsSource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1274 composition records across product categories including Cleaning products and household care, Personal care, Raw materials. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Cleaning agent, Softener and conditioner.
    • EPA CPDat observed this chemical in 1274 composition records across product categories including Cleaning products and household care, Personal care, Raw materials. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Cleaning agent, Softener and conditioner.Source →
  • USFDAinactive ingredient databaseRoute: TOPICAL; Dosage form: SHAMPOO; Potency: 1 %w/w
    • Route: TOPICAL; Dosage form: SHAMPOO; Potency: 1 %w/wSource →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as mixture.
    • openFDA substance registry classifies this ingredient as mixture.Source →

Expert safety opinions

No expert opinion on file for Sodium cocoyl isethionate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Sodium cocoyl isethionate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated september 19, 2012

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Sodium cocoyl isethionate in a product composition. These are source records, not Greenveil catalog products.

Source records

1,274

Named organisations

6

Cleaning products and household carePersonal careRaw materials

Typical roles

CleansingHair conditioningSurfactantConditionerCleaning agent
See products using Sodium cocoyl isethionate →

Catalog

Found in these products

Their ingredient lists include Sodium cocoyl isethionate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 263 →Find products without it →