beauty
cleaning
food
industrial

Calcium chloride

CAS 10035-04-8 · 0/100 · High conf.

Concern score

0/100Low concern — well-established and permitted without restriction (FDA GRAS; JECFA ADI not specified; EU food additive; EU CosIng).

High confidence

Calcium chloride in plain language

What it is: Also known as Calcium chloride dihydrate · Calcium chloride hydrate · Calcium dichloride dihydrate · Calcium chloride--water (1/2/2) · calcium;dichloride;dihydrate · AKOS024457459
Show all 26 names
Acs calcium chloride dihydrate · CaCl2.2H2O · Cal Plus · Calcium chloride (CaCl2), dihydrate · Calcium chloride (USP) · Calcium chloride dihydrate, ACS reagent, >=99% · Calcium chloride dihydrate, AR, >=98% · Calcium chloride dihydrate, BioXtra, >=99.0% · Calcium chloride dihydrate, LR, >=97% · Calcium chloride dihydrate, USP, 99.0-107.0% · Calcium chloride dihydrate, p.a. · Calcium chloride hydrate (JP18) · Calcium chloride, meets USP testing specifications · Conclyte-Ca (TN) · D02256 · PD079403 · TN9583 · UNII-M4I0D6VV5M · Calcarea muriatica · Multibic component calcium chloride dihydrate
What it does: Used in consumer products as a fragrance ingredient and a stabiliser.
Fragrance
Stabiliser
Is it a concern?: Low concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 52 composition records across product categories including Laboratory supplies, Food and drug, Landscape/yard.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Calcium chloride appears in these published regulatory listings.

In marketed US drugs
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Pharma
Food
Industrial

USFDAinactive ingredient database16 entries — 11 administration routes
- Route: INFILTRATION; Dosage form: INJECTION; Potency: 0.33 mgSource →
- Route: INTRA-ARTERIAL; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 11 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 4 %w/vSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Potency: 0.01 %w/vSource →
- Route: INTRAOCULAR; Dosage form: SOLUTION; Maximum daily exposure: 24 mgSource →
- Route: INTRAPERITONEAL; Dosage form: SOLUTION; Potency: 0.03 %w/vSource →
- Route: INTRATHECAL; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTABLE, LIPOSOMAL; Potency: 0.03 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 4 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 11 mgSource →
- Route: INTRAVITREAL; Dosage form: INJECTION, SUSPENSION; Potency: 0.05 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION; Maximum daily exposure: 1 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 0.02 %w/vSource →
- Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 2 mgSource →
- Route: ORAL; Dosage form: CONCENTRATE; Potency: 0.08 mg/1mlSource →
- Route: RESPIRATORY (INHALATION); Dosage form: CAPSULE; Maximum daily exposure: 3 mgSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 52 composition records across product categories including Laboratory supplies, Food and drug, Landscape/yard. EPA CPDat classifies this chemical for functional uses including Fragrance, Chemical reaction regulator, Processing aids not otherwise specified.
- EPA CPDat observed this chemical in 52 composition records across product categories including Laboratory supplies, Food and drug, Landscape/yard. EPA CPDat classifies this chemical for functional uses including Fragrance, Chemical reaction regulator, Processing aids not otherwise specified.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 127 active drug products and 152 total products.
- FDA NDC lists this ingredient in 127 active drug products and 152 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Calcium chloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
JECFA
Joint FAO/WHO Expert Committee on Food Additives
No JECFA evaluation on file.
EFSA
European Food Safety Authority
No EFSA opinion on file.

Evidence & sources

No graded research studies for Calcium chloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

EPA Chemical and Products Database
exposure · updated 2020-03-19
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2028-12-07
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often FDA National Drug Code directory has listed Calcium chloride in a product composition. These are source records, not Greenveil catalog products.

Source records

152

Typical roles

FragranceStabiliser

See products using Calcium chloride →

Catalog

Found in these products

Their ingredient lists include Calcium chloride; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 202 →Find products without it →