Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
- industrial
Cocarboxylase chloride
CAS 55056-45-6
Also registered as 3 other CAS numbers
74992-00-0 · 902463-63-2 · 154-87-0
Concern score
Not assessed — no hazard data yet.
Cocarboxylase chloride in plain language
On cosmetic ingredient lists it appears as “Thiamine diphosphate”.
Also known as Thiamine diphosphate · Cocarboxylase hydrochloride · Cocarboxylase · Cocarboxylase (INN:DCF:JAN) · Thiamine diphosphate ester chloride · Thiamine diphosphoric acid ester chloride
Show all 25 names
Thiamine pyrophosphate chloride · Thiamine pyrophosphate hydrochloride · Thiamine pyrophosphoric acid ester chloride · Aneurinepyrophosphoric acid · B-Neurox · Berolase · Biosyth · Bioxilasi · Bioxylasi · Bivitasi · Cocarbina · Cocarboxil · Cocarboxilasa · Cocarboxylasum · Coenbione · Farmaneurina · Pyruvodehydrase · Vitamin B1 pyrophosphate chloride · thiamine diphosphate chloride
Used in cosmetics as a skin-conditioning agent.
- Skin conditioning
- Conditioner
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Cocarboxylase chloride appears in these published regulatory listings.
- Found in consumer products
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Cocarboxylase chloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Cocarboxylase chloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated 30 November 2009
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context
Where it has been recorded
How often EPA CPDat has listed Cocarboxylase chloride in a product composition. These are source records, not Greenveil catalog products.
Named organisations
2
Typical roles
Skin conditioningConditioner
Found in these products
Cosmetic and personal-care products that list Cocarboxylase chloride are shown first. Their ingredient lists include Cocarboxylase chloride; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
