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Sodium sesquicarbonate

E500 · CAS 72227-05-5

Also registered as 4 other CAS numbers

8014-64-0 · 2270871-68-4 · 2423955-66-0 · 533-96-0

Sodium sesquicarbonate chemical structure

Concern score

Not assessed — no hazard data yet.

Sodium sesquicarbonate in plain language

What it is

Also known as Carbonic acid, sodium salt (2:3) · Magadi soda · Snowflake crystals · Sodium-salt of carbonic acid · Sq 810 · Sodium carbonate hydrogen carbonate (3/1/1)

Show all 29 names

trisodium;hydrogen carbonate;carbonate · E-500(III) · Hydrogenodicarbonate de trisodium · Ins NO.500(III) · INS-500(III) · Natriumsesquicarbonat · Sodium monohydrogendicarbonate · Solvay t 200 · SQ 810 Bulk · Sesqui TM · Snowfine · Sodium carbonate (3:2) · Trisodium hydrogendicarbonate · Trona · Urao · hidrogenodicarbonato de trisodio · sodium sesqicarbonate (10-15%) · sodium sesqui carbonate · sodium sesquicarbonate (10-15%) · sodium sesquicarbonate (na2co3.nahco3) · sodium sesquicarbonate cas# 533-96-0 · sodium sesquicarbonate castable · SQ-810

What it does

Used in cosmetics as a cleansing agent, a pH buffer and a bulking agent.

  • Cleansing
  • Buffering
  • Bulking
  • Chelating agent
  • pH adjuster
  • Cleaning agent
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

As a food additive

E-number
E500
Used in food as
  • Raising agent
  • Acidity regulator
  • Anti-caking agent
EU safety status

Authorised in the EU without a numerical limit (Group I); EFSA re-evaluation not yet published.

It never counts as an additive of concern in a product’s food rating.

Regulation (EC) No 1333/2008, Annex II Part C(1) Group I (quantum satis)

Regulation

No restrictions found. Sodium sesquicarbonate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 117 composition records across product categories including Cleaning and safety, Batteries, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Cleaning agent, Filler.
    • EPA CPDat observed this chemical in 117 composition records across product categories including Cleaning and safety, Batteries, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Cleaning agent, Filler.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Sodium sesquicarbonate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Sodium sesquicarbonate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

codexalimentarius.net

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Sodium sesquicarbonate in a product composition. These are source records, not Greenveil catalog products.

Source records

117

Named organisations

6

Cleaning and safetyBatteriesSpecialty occupational productsLaboratory suppliesCleaning products and household careHome maintenance

Typical roles

CleansingBufferingBulkingChelating agentpH adjusterCleaning agent
See products using Sodium sesquicarbonate →

Catalog

Found in these products

Cosmetic and personal-care products that list Sodium sesquicarbonate are shown first. Their ingredient lists include Sodium sesquicarbonate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.