Skip to content
  • beauty
  • cleaning
  • industrial

Pentafluoropropane

CAS 220035-33-6

Also registered as 1 other CAS number

460-73-1

Pentafluoropropane chemical structure

Concern score

Not assessed — no hazard data yet.

Pentafluoropropane in plain language

What it is

Also known as 1,1,1,3,3-Pentafluoropropane · 1,1,1,3,3,3-Pentafluoropropane · Enovate 3000 · F 245fa · Hfc 245A · HFC-245FA

Show all 11 names

HFC245A · Propane, 1,1,1,3,3,3-pentafluoro- · Propane, 1,1,1,3,3-pentafluoro- · R-245fa · UNII-TA9UOF49CY

What it does

Used in cosmetics as a solvent, a propellant and a fragrance ingredient.

  • Solvent
  • Propellant
  • Fragrance
  • Deodorant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Pentafluoropropane appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 37 composition records across product categories including Personal care, Home maintenance, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Solvent, Propellants, non-motive (blowing agents), Deodorizer.
    • EPA CPDat observed this chemical in 37 composition records across product categories including Personal care, Home maintenance, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Solvent, Propellants, non-motive (blowing agents), Deodorizer.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Pentafluoropropane. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Pentafluoropropane yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated january 30, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

msds.chem.ox.ac.uk

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Pentafluoropropane in a product composition. These are source records, not Greenveil catalog products.

Source records

37

Named organisations

6

Personal careHome maintenanceConstruction and building materialsRaw materialsElectronics/small appliances

Typical roles

SolventPropellantFragranceDeodorant
See products using Pentafluoropropane →

Catalog

Found in these products

Cosmetic and personal-care products that list Pentafluoropropane are shown first. Their ingredient lists include Pentafluoropropane; each product's own rating depends on its whole formula, so it is shown on the product page, not here.