Food use
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
- cleaning
- pharma
Hexamidine diisethionate
CAS 659-40-5
Concern score
Not assessed — no hazard data yet.
Hexamidine diisethionate in plain language
Also known as Hexamidine isetionate · Hexamidine diisetionate · Hexamidine isethionate · 2535RP · 4,4'-(HEXAMETHYLENEDIOXY)DIBENZAMIDINE isethionate · Benzamidine, 4,4'-(hexamethylenedioxy)di-, diisethionate
Show all 14 names
Desomedine · Esomedina · Hexomedin · Hexomedin N · Hexomedine · Laryngomedin N · Ophtamedine · RF-2535
Used in consumer products as a preservative, a conditioner and an antimicrobial.
- Preservative
- Conditioner
- Antimicrobial
- We haven't assessed a concern score for this ingredient yet.
Regulation
No restrictions found. Hexamidine diisethionate appears in these published regulatory listings.
- In marketed US drugs
- Found in consumer products
- Beauty
- Cleaning
USEPAcommercial use observedEPA CPDat observed this chemical in 23 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Preservative, Defoamer.
- EPA CPDat observed this chemical in 23 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Preservative, Defoamer.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
- FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Hexamidine diisethionate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Hexamidine diisethionate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
EPA Chemical and Products Database
exposure · updated November 2014
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often EPA CPDat has listed Hexamidine diisethionate in a product composition. These are source records, not Greenveil catalog products.
Source records
23
Named organisations
6
Personal care
Typical roles
PreservativeConditionerAntimicrobial
Found in these products
Their ingredient lists include Hexamidine diisethionate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
