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D&C blue no. 4

CAS 2650-18-2

Also registered as 2 other CAS numbers

6371-85-3 · 37307-56-5

Concern score

Not assessed — no hazard data yet.

D&C blue no. 4 in plain language

What it is

On cosmetic ingredient lists it appears as “Acid blue 9 ammonium salt”.

Also known as Acid blue 9 ammonium salt · Blue 4 · Dc blue no. 4 · Dye dc blue no. 4

What it does

Used in cosmetics as a hair dye. Acid Blue 9 Ammonium Salt is classed chemically as a triphenylmethane colour.

  • Hair dyeing
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

Regulation

No restrictions found. D&C blue no. 4 appears in these published regulatory listings.

  • EUCosIngActiveAcid Blue 9 Ammonium Salt is classed chemically as a triphenylmethane colour. It conforms to the formula: Restriction: III/190
    • Acid Blue 9 Ammonium Salt is classed chemically as a triphenylmethane colour. It conforms to the formula: Restriction: III/190Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as mixture.
    • openFDA substance registry classifies this ingredient as mixture.Source →

Expert safety opinions

No expert opinion on file for D&C blue no. 4. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for D&C blue no. 4 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.