# SILICONE QUATERNIUM-28

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid701363943
Categories: beauty
Functions: Hair conditioning
Identifier: DTXSID701363943

> SILICONE QUATERNIUM-28: Used in cosmetics as a hair conditioner. EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical. Compiled from 2 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

## Regulatory status

- EU: Active — Silicone Quaternium-28 is the polysiloxane quaternary ammonium salt formed by the reaction of glycidoxy-terminated dimethicone, glycidoxy-terminated PEG-5, and tetramethyl hexamethylene diamine in the presence of Lauric Acid.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/96527
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566

_Assessed by Greenveil._