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Spinorphin

CAS 137201-62-8

Concern score

Not assessed — no hazard data yet.

Spinorphin in plain language

What it is

On cosmetic ingredient lists it appears as “Sh-spinorphin sp”.

Also known as Sh-spinorphin sp · Leu-val-val-tyr-pro-trp-thr · Leucyl-valyl-valyl-tyrosyl-prolyl-tryptophyl-threonine

What it does

Used in cosmetics as a skin protectant.

  • Skin protecting
  • Humectant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Spinorphin appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActivesh-Spinorphin SP is a single chain protein produced synthetically to be identical to Spinorphin, which is a 7 amino acid peptide from the parent protein, Hemoglobin Subunit Beta. Hemoglobin Subunit Beta contains 147 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
    • sh-Spinorphin SP is a single chain protein produced synthetically to be identical to Spinorphin, which is a 7 amino acid peptide from the parent protein, Hemoglobin Subunit Beta. Hemoglobin Subunit Beta contains 147 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.Source →

Expert safety opinions

No expert opinion on file for Spinorphin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Spinorphin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

3 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2019-12-20

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Spinorphin in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Skin protectingHumectant
See products using Spinorphin →