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Biotinoyl TRIPEPTIDE-1

CAS 299157-54-3

Biotinoyl TRIPEPTIDE-1 chemical structure

Concern score

Not assessed — no hazard data yet.

Biotinoyl TRIPEPTIDE-1 in plain language

What it is

Also known as Biotin-ghk · Bio-GHK · Biotin Tripeptide-1(acetate) · Biotinoyl GHK · Biotinoyl-Tripeptide-1, TFA salt · BiotinoylTripeptide-1?

Show all 12 names

Biotinoylglycylhistidyllysine · CIG-83 · EX-A15807 · TP2373 · UNII-O6380721VA · Wckvvoduwgbpqv-soadlsrisa-n

What it does

Used in cosmetics as a hair conditioner.

  • Hair conditioning
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Biotinoyl TRIPEPTIDE-1 appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUCosIngActiveBiotinoyl Tripeptide-1 is the reaction product of Biotin and Tripeptide-1.
    • Biotinoyl Tripeptide-1 is the reaction product of Biotin and Tripeptide-1.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 32 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 32 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 1 total products.
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Biotinoyl TRIPEPTIDE-1. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Biotinoyl TRIPEPTIDE-1 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Biotinoyl TRIPEPTIDE-1 in a product composition. These are source records, not Greenveil catalog products.

Source records

32

Named organisations

6

Personal care

Typical roles

Hair conditioningConditioner
See products using Biotinoyl TRIPEPTIDE-1 →

Catalog

Found in these products

Their ingredient lists include Biotinoyl TRIPEPTIDE-1; each product's own rating depends on its whole formula, so it is shown on the product page, not here.