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Aspartic acid

CAS 56-84-8 · 60/100 · High conf.

Also registered as 3 other CAS numbers

6899-03-2 · 181119-33-5 · 2139279-07-3

Aspartic acid chemical structure

Concern score

60/100High concern based on regulatory listings.
High confidence

Aspartic acid in plain language

What it is

Also known as L-aspartic acid · (2S)-2-aminobutanedioic acid · Aspartic acid, l- · Deamidated asparagine · (+)-Aspartic acid · (S)-2-Aminobutanedioic acid

Show all 26 names

(S)-2-Aminosuccinic acid · (S)-Aminobutanedioic acid · (S)-Aspartic acid · 2-Aminobutanedioic acid · 2-aminosuccinic acid · Acide aspartique · Acidum asparticum · Aminosuccinic acid · Asparagic acid · Asparaginic acid · Asparaginsaeure · Butanedioic acid, amino-, (S)- · L-(+)-Aspartic acid · L-Aminosuccinic acid · L-Asparagic acid · L-Asparaginic acid · L-Asparaginsaeure · acido aspartico · aspartate · l-asparatic

What it does

Used in food as a flavouring agent.

  • Flavouring agent
  • pH adjuster
  • Flavouring
Is it a concern?
High concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 13 composition records across product categories including Food and drug, Raw materials, Laboratory supplies.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Aspartic acid appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Pharma
  • Food
  • Industrial
  • EUEFSAEFSA opinion3 entries
    • Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species (EFSA FEEDAP)Source →
    • Flavouring Group Evaluation 79, (FGE.79). Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)Source →
    • Magnesium aspartate, potassium aspartate, magnesium potassium aspartate, calcium aspartate, zinc aspartate, and copper aspartate as sources for magnesium, potassium, calcium, zinc, and copper added for nutritional purposes to food supplements (EFSA ANS)Source →
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 13 composition records across product categories including Food and drug, Raw materials, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 13 composition records across product categories including Food and drug, Raw materials, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 17 active drug products and 18 total products.
    • FDA NDC lists this ingredient in 17 active drug products and 18 total products.Source →
  • USFDAinactive ingredient databaseRoute: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 22 mg
    • Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 22 mgSource →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

  • EFSA

    European Food Safety Authority

    • Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species (EFSA FEEDAP)

      2014 · EU EFSA listing · Read the source →

    • Flavouring Group Evaluation 79, (FGE.79). Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (EFSA AFC)

      2008 · EU EFSA listing · Read the source →

    • Magnesium aspartate, potassium aspartate, magnesium potassium aspartate, calcium aspartate, zinc aspartate, and copper aspartate as sources for magnesium, potassium, calcium, zinc, and copper added for nutritional purposes to food supplements (EFSA ANS)

      2008 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Aspartic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated november 12, 2010

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Aspartic acid in a product composition. These are source records, not Greenveil catalog products.

Source records

18

Typical roles

Flavouring agentpH adjusterFlavouring
See products using Aspartic acid →

Catalog

Found in these products

Their ingredient lists include Aspartic acid; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 137 →Find products without it →