Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
4,4'-Diphenylmethane diisocyanate
EPA CPDat observed this chemical in 770 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning products and household care.
Research docs0Claims0Sources5FunctionAdhesion/cohesion promoter • BinderIdentifierDTXSID7025180
Concern score
Not assessed — no hazard data yet.
How we scored this
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 5/100 · limited confidence.
Where it appears
Prevalence of 4,4'-Diphenylmethane diisocyanate in our catalog (epa_cpdat).
Products
770
Brands
6
Construction and building materialsFurniture and furnishingsCleaning products and household careConstructionRaw materialsHome maintenance
Typical roles
Adhesion/cohesion promoterBinderCatalystcrosslinking / coupling / curing agents > diisocyanates
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Evidence read
The published evidence profile currently shaping this ingredient record.
No evidence profiles are attached to this ingredient yet.
Linked research
Primary documents currently linked to this ingredient record.
No linked research documents are attached to this ingredient yet.
Extracted claims
Structured claim signals pulled from linked ingredient research.
No extracted claims are attached to this ingredient yet.
Regulatory status
Published jurisdiction-level classifications and regulatory designations for this ingredient.
US
EPA
EPA CPDat observed this chemical in 770 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including No specific technical function, Binder, Hardener.
Effective: september-02-2015View source →
US
FDA
openFDA substance registry classifies this ingredient as chemical.
Effective: 2026-05-24View source →