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  • beauty
  • cleaning
  • food
  • industrial

Isomethyl-.alpha.-ionone

CAS 127-51-5 · 40/100 · High conf.

Isomethyl-.alpha.-ionone chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Isomethyl-.alpha.-ionone in plain language

What it is

Also known as .alpha.-isomethylionone · Isomethyl-alpha-ionone · alpha-CETONE · alpha-ISO-METHYLIONONE · alpha-Isomethylionone · Alpha-isomethyl ionone

Show all 22 names

(±)-isomethyl-.alpha.-ionone · .alpha.-cetone · .alpha.-ionone, isomethyl- · 3-Methyl-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-en-2-one · Alphaisomethyl ionone · Cetone alpha · Isomethylionone (alpha-) · Methyl .gamma.-ionone · (+/-)-isomethyl-.alpha.-ionone · 4-(2,6,6-TRIMETHYL-2-CYCLOHEXEN-1-YL)-3-METHYL-3-BUTEN-2-ONE · Alpha-Isomethyl Lonone · Isomethyl-α-ionone · iso raldine 70 · methyl ionone, alpha-iso- · α-Cetone · α-Ionone, isomethyl-

What it does

Used in food as a flavouring agent.

  • Flavouring agent
  • Fragrance
  • Flavouring
  • Conditioner
  • Deodorant
Is it a concern?
Moderate concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 2171 composition records across product categories including Personal care, Cleaning products and household care, Vehicle.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Isomethyl-.alpha.-ionone appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2171 composition records across product categories including Personal care, Cleaning products and household care, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Softener and conditioner, Deodorizer.
    • EPA CPDat observed this chemical in 2171 composition records across product categories including Personal care, Cleaning products and household care, Vehicle. EPA CPDat classifies this chemical for functional uses including Fragrance, Softener and conditioner, Deodorizer.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3 drug products and 3 package presentations.
    • FDA NDC lists this ingredient in 3 drug products and 3 package presentations.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Isomethyl-.alpha.-ionone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated june 4, 2015

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-10-13

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Isomethyl-.alpha.-ionone in a product composition. These are source records, not Greenveil catalog products.

Source records

2,171

Named organisations

6

Personal careCleaning products and household careVehicleHome maintenanceConstructionPet and animal care

Typical roles

Flavouring agentFragranceFlavouringConditionerDeodorant
See products using Isomethyl-.alpha.-ionone →

Catalog

Found in these products

Their ingredient lists include Isomethyl-.alpha.-ionone; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1000+ →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Isomethyl-.alpha.-ionone in the catalog.