Skip to content

GREENVEIL

  • beauty
  • cleaning
  • industrial

Sodium isethionate

CAS 52117-27-8 · 0/100 · High conf.

Also registered as 2 other CAS numbers

78858-24-9 · 1562-00-1

Sodium isethionate chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe when formulated as directed; EU CosIng).
High confidence

Sodium isethionate in plain language

What it is

Also known as Sodium 2-hydroxyethanesulfonate · 2-HYDROXYETHANESULFONIC acid, sodium salt · Ethanesulfonic acid, 2-HYDROXY-, monosodium salt · Sodium salt isethionate · Sodium 2-hydroxyethane-1-sulfonate · 2-Hydroxyethanesulfonate de sodium

Show all 23 names

2-Hydroxyethanesulfonic acid monosodium salt · 2-Hydroxyethanesulfonic acid sodium salt · 2-hidroxietanosulfonato de sodio · Adeka Tec HES · C2H5NaO4S · Ethanesulfonate, 2-HYDROXY-, sodium · Ethanesulfonic acid, 2-hydroxy-, sodium salt · Ethanesulfonic acid, 2-hydroxy-, sodium salt (1:1) · Isethionic acid sodium salt · Sodium 2-HYDROXYETHANESULFONIC acid · Sodium 2-hydroxy-1-ethanesulfonate · Sodium 2-hydroxyethanesulphonate · Sodium 2-hydroxyethyl sulfonate · Sodium 2-hydroxyethylsulfonate · Sodium beta-hydroxyethanesulfonate · Sodium hydroxyethylsulfonate · sodiumbeta-hydroxyethanesulfonate

What it does

Used in cosmetics as a skin-conditioning agent, a cleansing agent and a hair conditioner.

  • Skin conditioning
  • Cleansing
  • Hair conditioning
  • Antistatic
  • Surfactant
  • Conditioner
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 280 composition records across product categories including Laboratory supplies, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Sodium isethionate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 280 composition records across product categories including Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner, Cleaning agent.
    • EPA CPDat observed this chemical in 280 composition records across product categories including Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Anti-static agent, Softener and conditioner, Cleaning agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Sodium isethionate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Sodium isethionate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated october 1, 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Sodium isethionate in a product composition. These are source records, not Greenveil catalog products.

Source records

280

Named organisations

6

Laboratory suppliesPersonal care

Typical roles

Skin conditioningCleansingHair conditioningAntistaticSurfactantConditioner
See products using Sodium isethionate →

Catalog

Found in these products

Their ingredient lists include Sodium isethionate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 170 →Find products without it →