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Somatropin

CAS 12629-01-5

Concern score

Not assessed — no hazard data yet.

Somatropin in plain language

What it is

On cosmetic ingredient lists it appears as “RH-POLYPEPTIDE-7”.

Also known as RH-POLYPEPTIDE-7 · Human growth hormone · Somatotropin · Somatotropin human growth hormone · Somatropin (recombinant DNA origin) · Somatropin recombinant

Show all 41 names

Growth hormone · Growth hormone (human) · R-hgh · Recombinant human growth hormone · Somatotropin human · Somatropin (rdna origin) · Somatropin(recombinant DNA origin) · Bio-Tropin · CB-311 · Corpormon · Crescormon · Genotonorm · Genotropin · Hgh · Hsb-hgh · Hypertropin · Humatrope · Infitropin CR · LY-137998 · LY137998 · Nutropin · Nutropinaq · Norditropin · Omnitrope · Saizen · Serostim · Somatropin biopartners · Somatotropin (human) · Tev-tropin · Tevtropin · Valtropin · Vexxon-hgh · Zomacton · Zorbtive · Somatropin for injection

What it does

Used in cosmetics as a humectant, a skin-conditioning agent and a skin protectant.

  • Humectant
  • Skin conditioning
  • Skin protecting
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Somatropin appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Pharma
  • Food
  • EUCosIngActiverh-Polypeptide-7 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Human Growth Hormone. It contains a maximum of 217 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416
    • rh-Polypeptide-7 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Human Growth Hormone. It contains a maximum of 217 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 13 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner.
    • EPA CPDat observed this chemical in 13 composition records across product categories including Food and drug. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 22 active drug products and 35 total products.
    • FDA NDC lists this ingredient in 22 active drug products and 35 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
    • openFDA substance registry classifies this ingredient as protein.Source →

Expert safety opinions

No expert opinion on file for Somatropin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Somatropin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 30-Jun-16

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2028-12-11

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (6)
Openfda substance

mri.medagencies.org

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Somatropin in a product composition. These are source records, not Greenveil catalog products.

Source records

35

Typical roles

HumectantSkin conditioningSkin protectingConditioner
See products using Somatropin →