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Disodium pyrophosphate

CAS 10101-84-5 · 40/100 · High conf.

Also registered as 1 other CAS number

7758-16-9

Disodium pyrophosphate chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Disodium pyrophosphate in plain language

What it is

Also known as Sodium acid pyrophosphate · Dinatriumpyrophosphat · Disodium dihydrogen diphosphate · Disodium dihydrogen pyrophosphate · Sodium pyrophosphate · Dihydrogen disodium pyrophosphate

Show all 18 names

Dihydrogenopyrophosphate de disodium · Dinatriumdihydrogenpyrophosphat · sodium salt Diphosphoric acid · Diphosphoric acid, sodium salt (1:2) · Disodium acid pyrophosphate · Disodiumpytophosphate · Sapp · Sodium diphosphate dibasic · Sodium pyrophosphate (Na2H2P2O7) · UNII-H5WVD9LZUD · dihidrogenopirofosfato de disodio · disodium hydrogen (hydrogen phosphonatooxy)phosphonate

What it does

Used in cosmetics as an anticorrosive, a pH buffer and a chelating agent.

  • Anticorrosive
  • Buffering
  • Chelating
  • Acidity regulator, raising agent, sequestrant
  • Emulsifier
  • Chelating agent
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 96 composition records across product categories including Cleaning and safety, Personal care, Specialty occupational products.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Disodium pyrophosphate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • GLOBALJECFAEvaluated2 entries
    • JECFA evaluation record. Functional class: acidity regulator, raising agent, sequestrant.Source →
    • JECFA evaluation record.Source →
  • EUCosIngActiveDisodium dihydrogenpyrophosphate
  • EUEFSAEFSA opinionScientific Opinion on the safety evaluation of the active substances, iron, polyethyleneglycol, disodium pyrophosphate, monosodium phosphate and sodium chloride for use in food contact materials (EFSA CEF)
    • Scientific Opinion on the safety evaluation of the active substances, iron, polyethyleneglycol, disodium pyrophosphate, monosodium phosphate and sodium chloride for use in food contact materials (EFSA CEF)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 96 composition records across product categories including Cleaning and safety, Personal care, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Chelating agent, Corrosion inhibitor.
    • EPA CPDat observed this chemical in 96 composition records across product categories including Cleaning and safety, Personal care, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Chelating agent, Corrosion inhibitor.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Scientific Opinion on the safety evaluation of the active substances, iron, polyethyleneglycol, disodium pyrophosphate, monosodium phosphate and sodium chloride for use in food contact materials (EFSA CEF)

      2013 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record. Functional class: acidity regulator, raising agent, sequestrant.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Disodium pyrophosphate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated July 2016

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Disodium pyrophosphate in a product composition. These are source records, not Greenveil catalog products.

Source records

96

Named organisations

6

Cleaning and safetyPersonal careSpecialty occupational products

Typical roles

AnticorrosiveBufferingChelatingAcidity regulator, raising agent, sequestrantEmulsifierChelating agent
See products using Disodium pyrophosphate →

Catalog

Found in these products

Cosmetic and personal-care products that list Disodium pyrophosphate are shown first. Their ingredient lists include Disodium pyrophosphate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 128 →Find products without it →