Skip to content
  • beauty
  • cleaning

Esculin

CAS 25360-17-2

Also registered as 5 other CAS numbers

28633-38-7 · 29008-74-0 · 97882-87-6 · 1078728-35-4 · 531-75-9

Esculin chemical structure

Concern score

Not assessed — no hazard data yet.

Esculin in plain language

What it is

Also known as Esculoside · 6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE · 7-Hydroxy-2-oxo-2H-1-benzopyran-6-yl beta-D-glucopyranoside · Aesculin · Bicolorin · Enallachrome

Show all 22 names

Escosyl · Esculina · Polychrome · (-)-Esculin · 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy- · 6,7-Dihydroxycoumarin-6-O-glucoside · 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-cumarin · 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one · 6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin · 7-Hydroxy-6-cumarinyl-glucosid · 7-hydroxy-2-oxo-2H-chromen-6-yl beta-D-glucopyranoside · Crataegin · Esculetin 6-O-glucoside · Esculetin 6-beta-D-glucoside · aesculine · Aesculinum

What it does

Used in cosmetics as a tonic and a light stabiliser. Esculin is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree, Aesculus hippocastanum.

  • Tonic
  • Light stabilizer
  • Humectant
  • Stabiliser
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Esculin appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveEsculin is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree, Aesculus hippocastanum. It conforms to the formula
    • Esculin is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree, Aesculus hippocastanum. It conforms to the formulaSource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 10 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Stabilizing agent.
    • EPA CPDat observed this chemical in 10 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Stabilizing agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Esculin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Esculin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated march 22, 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Esculin in a product composition. These are source records, not Greenveil catalog products.

Source records

10

Named organisations

6

Personal care

Typical roles

TonicLight stabilizerHumectantStabiliser
See products using Esculin →

Catalog

Found in these products

Their ingredient lists include Esculin; each product's own rating depends on its whole formula, so it is shown on the product page, not here.