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Naphazoline hcl

CAS 35412-62-5

Also registered as 1 other CAS number

550-99-2

Naphazoline hcl chemical structure

Concern score

Not assessed — no hazard data yet.

Naphazoline hcl in plain language

What it is

Also known as Naphazoline hydrochloride · 2-(1-NAPHTHYLMETHYL)-2-IMIDAZOLINE monohydrochloride · 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride · 2-(α-Naphthylmethyl)-2-imidazoline hydrochloride · 2-Imidazoline, 2-(1-naphthylmethyl)-, monohydrochloride · Albalon

Show all 26 names

Ak-Con · Allerest Eye Drops · Clera · Coldan · Nafazair · Naphcon forte · Naphazoline chloride · Niazol · Opcon · Privine hydrochloride · Prizole hydrochloride · Rhinantin · Rhinoperd · Sanorin · Stricylon · Vasocon · Naphcon-a component naphazoline hydrochloride · Opcon-a component naphazoline hydrochloride · Vasocon-a component naphazoline hydrochloride · Visine-a component naphazoline hydrochloride

What it does

Used in cosmetics as a skin-conditioning agent. Naphazoline HCL is the heterocyclic compound.

  • Skin conditioning
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

Regulation

No restrictions found. Naphazoline hcl appears in these published regulatory listings.

  • In marketed US drugs
  • EUCosIngActiveNaphazoline HCL is the heterocyclic compound that conforms to the formula Restriction: II/244
    • Naphazoline HCL is the heterocyclic compound that conforms to the formula Restriction: II/244Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 67 active drug products and 67 total products.
    • FDA NDC lists this ingredient in 67 active drug products and 67 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Naphazoline hcl. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Naphazoline hcl yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Naphazoline hcl in a product composition. These are source records, not Greenveil catalog products.

Source records

67

Typical roles

Skin conditioning
See products using Naphazoline hcl →