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Carglumic acid

CAS 1188-38-1

Also registered as 1 other CAS number

52093-31-9

Carglumic acid chemical structure

Concern score

Not assessed — no hazard data yet.

Carglumic acid in plain language

What it is

On cosmetic ingredient lists it appears as “Carbamylglutamic acid”.

Also known as Carbamylglutamic acid · N-Carbamyl-L-glutamic acid · (2S)-2-(carbamoylamino)pentanedioic acid · L-glutamic acid, n-(aminocarbonyl)- · N-Carbamoyl-L-glutamic acid · (S)-2-ureidopentanedioic acid

Show all 16 names

Carbamyl-l-glutamic acid · Carbaglu · Carbamino-L-glutamic acid · L-N-Carbamoylglutamic acid · N-carbamylglutamate · Oe 312 · Ureidoglutaric acid · acide carglumique · acido carglumico · acidum carglumicum

What it does

Used in cosmetics as an antioxidant, a humectant and a skin-conditioning agent.

  • Antioxidant
  • Humectant
  • Skin conditioning
  • Hair conditioning
  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Carglumic acid appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveCarbamylglutamic Acid is the organic compound that conforms to the formula
    • Carbamylglutamic Acid is the organic compound that conforms to the formulaSource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 4 active drug products and 4 total products.
    • FDA NDC lists this ingredient in 4 active drug products and 4 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Carglumic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Carglumic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 30-Jun-16

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (4)
Openfda substance

business.highbeam.com

Openfda substance

accessdata.fda.gov

Openfda substance

accessdata.fda.gov

Openfda substance

clinicalkey.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Carglumic acid in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Typical roles

AntioxidantHumectantSkin conditioningHair conditioningSkin protecting
See products using Carglumic acid →