Food use
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
- cleaning
- food
- industrial
Guanidine hcl
CAS 420-13-3
Also registered as 10 other CAS numbers
14317-32-9 · 15827-40-4 · 87667-20-7 · 94369-44-5 · 106946-18-3 · 139693-44-0 · 143504-22-7 · 915070-50-7 · 1340579-42-1 · 50-01-1
Concern score
Not assessed — no hazard data yet.
Guanidine hcl in plain language
Also known as Guanidine hydrochloride · Guanidine monohydrochloride · Guanidinium chloride · Guanidine--hydrogen chloride (1/1) · guanidine;hydrochloride · Aminoformamidine hydrochloride
Show all 20 names
Aminomethanamidine hydrochloride · Buffer AL · Carbamidine hydrochloride · Guanidium Chloride · Chlorure de guanidinium · Guanidin.hcl · Guanidine chloride · Guanidine, hydrochloride (1:1) · monohydrochloride Guanidine · Guanidinehydrochloride · Iminourea hydrochloride · cloruro de guanidinio · guanidine hydrogen chloride · monohydrochloride
Used in cosmetics as a pH buffer.
- Buffering
- pH adjuster
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. Guanidine hcl appears in these published regulatory listings.
- Found in consumer products
- Beauty
- Cleaning
- Pharma
- Food
- Industrial
EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 39 composition records across product categories including Food and drug, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including pH regulating agent, No specific technical function.
- EPA CPDat observed this chemical in 39 composition records across product categories including Food and drug, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including pH regulating agent, No specific technical function.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Guanidine hcl. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Guanidine hcl yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EPA Chemical and Products Database
exposure · updated September 2013
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context
Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
Where it has been recorded
How often EPA CPDat has listed Guanidine hcl in a product composition. These are source records, not Greenveil catalog products.
Source records
39
Named organisations
4
Food and drugLaboratory suppliesPersonal care
Typical roles
BufferingpH adjuster