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Sodium monofluorophosphate

CAS 10163-15-2 · 20/100 · High conf.

Also registered as 3 other CAS numbers

7631-97-2 · 12331-99-6 · 69794-00-9

Sodium monofluorophosphate chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Sodium monofluorophosphate in plain language

What it is

Also known as Sodium fluorophosphate · Disodium monofluorophosphate · Disodium phosphorofluoridate · Disodium salt phosphorofluoridic acid · disodium;fluoro-dioxido-oxo-lambda5-phosphane · AGToothpaste

Show all 31 names

Barbie · Cloveden Tooth · DeCure · Extra-Strength Aim · Finefra Silver · MyntSmile · Orazen · Phoskadent Na 211 · Priyal · Regular · Rembrandt · Salivea · Sensodyne-Fluor · SmartMouth · Sodium fluorophosphate (Na2PFO3) · Sodium phosphorofluoridate · Sodium phosphorofluoridate ((NaO)2FPO) · Sodium phosphorofluoridate (Na2PO3F) · SparkleFresh · brident · purple tooth · smilecare · sodium monofluoroph osphate · sodium monofluoropho sphate · sodium monofluorophosphat e

What it does

Used in consumer products as an oral-care ingredient.

  • Oral care
Is it a concern?
Minor concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 24 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Sodium monofluorophosphate appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUEFSAEFSA opinionSodium monofluorophosphate as a source of fluoride added for nutritional purposes to food supplements (EFSA ANS)
    • Sodium monofluorophosphate as a source of fluoride added for nutritional purposes to food supplements (EFSA ANS)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 24 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Pharmaceutical, oral care, Oral Care Agent.
    • EPA CPDat observed this chemical in 24 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Pharmaceutical, oral care, Oral Care Agent.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 158 active drug products and 162 total products.
    • FDA NDC lists this ingredient in 158 active drug products and 162 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    • Sodium monofluorophosphate as a source of fluoride added for nutritional purposes to food supplements (EFSA ANS)

      2008 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Sodium monofluorophosphate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated July 2016

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2029-07-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Sodium monofluorophosphate in a product composition. These are source records, not Greenveil catalog products.

Source records

162

Typical roles

Oral care
See products using Sodium monofluorophosphate →

Catalog

Found in these products

Their ingredient lists include Sodium monofluorophosphate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Sodium monofluorophosphate in the catalog.