# SODIUM MONOFLUOROPHOSPHATE

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid70872554
Categories: beauty, food, pharma
Functions: Oral care
Identifier: DTXSID70872554

> SODIUM MONOFLUOROPHOSPHATE: Used in consumer products as an oral-care ingredient. Greenveil chemical-concern score: 20/100 — Minor concern based on regulatory listings.. Compiled from 7 published data sources.

## Safety assessment

- Chemical concern score: 20/100 — Minor concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Minor concern: no hazard classifications on record.
- Rationale: EPA CPDat observed this chemical in 24 composition records across product categories including Personal care.

## Regulatory status

- EU: EFSA opinion — Sodium monofluorophosphate as a source of fluoride added for nutritional purposes to food supplements (EFSA ANS)
- US: commercial use observed — EPA CPDat observed this chemical in 24 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Pharmaceutical, oral care, Oral Care Agent.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 158 active drug products and 162 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.
- JECFA (Joint FAO/WHO Expert Committee on Food Additives): no opinion on file.
- EFSA (European Food Safety Authority): Sodium monofluorophosphate as a source of fluoride added for nutritional purposes to food supplements (EFSA ANS) — 2008 — https://doi.org/10.2903/j.efsa.2008.886.

## Data sources

- EFSA OpenFoodTox (updated 2026-10-04): https://doi.org/10.5281/zenodo.8120114
- EPA Chemical and Products Database (updated July 2016): http://siri.org/msds/f2/bkj/bkjwh.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA National Drug Code Directory (updated 2029-07-31): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:C810JCZ56Q
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/24266

_Assessed by Greenveil._